PDB | 3pbl Structure of the human dopamine D3 receptor

Structure of the human dopamine D3 receptor in complex with eticlopride

label Keywords
structural genomics, psi-2, psi-biology, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, 7tm, g protein-coupled receptor, gpcr, gpcr network, signal transduction, hydrolase, eticlopride, dopamine, neurotransmitter, chimera, t4l fusion, membrane protein, transmembrane, hydrolase-hydrolase inhibitor complex
event_note Published
10/16/2024
blur_on Resolution
2.89 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide

Original publication

import_contacts Title
Structure of the human dopamine d3 receptor in complex with a d2/d3 selective antagonist.
import_contacts Journal
Science 2010
import_contacts DOI
10.1126/science.1197410
person Authors
Chien, E.Y., Hanson, M.A., Javitch, J.A., Cherezov, V., Zhao, Q., Han, G.W., Katritch, V., Newman, A.H., Shi, L., Stevens, R.C., Liu, W.

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