PDB | 3p0g Structure of a nanobody-stabilized active state of the beta2 adrenoceptor

Structure of a nanobody-stabilized active state of the beta2 adrenoceptor

label Keywords
beta-2 adrenoceptor, agonist, nanobody, 7tm, gpcr, membrane, signaling protein, hydrolase, membrane protein
event_note Published
10/30/2024
blur_on Resolution
3.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one

Original publication

import_contacts Title
Structure of a nanobody-stabilized active state of the b2 adrenoceptor
import_contacts Journal
Nature 2011
import_contacts DOI
10.1038/nature09648
person Authors
Thian, F.S., Sunahara, R.K., Gellman, S.H., Kobilka, B.K., Weis, W.I., Rasmussen, S.G., Chae, P.S., Konetzki, I., Fung, J.J., Choi, H.J., Schnapp, A., Kobilka, T.S., Rosenbaum, D.M., Steyaert, J., Pautsch, A., Pardon, E., Devree, B.T., Casarosa, P.

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