PDB | 3oe0 CXCR4 chemokine receptor
Crystal structure of the CXCR4 chemokine receptor in complex with a cyclic peptide antagonist CVX15
label Keywords
structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, 7tm, g protein-coupled receptor, gpcr, signal transduction, hydrolase, cancer, hiv-1 co-receptor, chemokine, cxcl12, chimera, t4l fusion, membrane protein, transmembrane, antimicrobial, antibiotic, polyphemusin, signaling protein, hydrolase-antibiotic complex, psi-biology, gpcr network
event_note Published
08/12/2010
blur_on Resolution
2.9 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
Original publication
import_contacts Title
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.
import_contacts Journal
Science 2010
import_contacts DOI
10.1126/science.1194396
person Authors
Chien, E.Y., Hamel, D.J., Mol, C.D., Bi, F.C., Wells, P., Cherezov, V., Kuhn, P., Fenalti, G., Katritch, V., Brooun, A., Wu, B., Stevens, R.C., Abagyan, R., Liu, W., Handel, T.M.
copyrightData provided by Research Collaboration for Structural Biology, Chien, E.Y., Hamel, D.J., Mol, C.D., Bi, F.C., Wells, P., Cherezov, V., Kuhn, P., Fenalti, G., Katritch, V., Brooun, A., Wu, B., Stevens, R.C., Abagyan, R., Liu, W., Handel, T.M. , provided free of copyright via the Protein DataBank. View original data or read license terms.
