PDB | 3ny8 Human beta2 adrenergic receptor
Crystal structure of the human beta2 adrenergic receptor in complex with the inverse agonist ICI 118,551
label Keywords
g protein-coupled receptor, lysozyme, fusion, transducer, adrenergic, g-proteins, arrestins, adrenalin, ici 118, 551, glycosylation, palmitoylation, phosphorylation, membrane protein, hydrolase, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, gpcr network, gpcr
event_note Published
11/27/2024
blur_on Resolution
2.84 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CHOLESTEROL, (2S,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]butan-2-ol, OLEIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, TRIETHYLENE GLYCOL
Original publication
import_contacts Title
Conserved Binding Mode of Human beta(2) Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography
import_contacts Journal
J.Am.Chem.Soc. 2010
import_contacts DOI
10.1021/ja105108q
person Authors
Cherezov, V., Brown, M.A., Fenalti, G., Katritch, V., Abagyan, R., Wacker, D., Stevens, R.C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Cherezov, V., Brown, M.A., Fenalti, G., Katritch, V., Abagyan, R., Wacker, D., Stevens, R.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
