PDB | 3jaf Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine/ivermectin-bound state
Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine/ivermectin-bound state
label Keywords
cys loop receptor, alpha-1 glycine receptor, glycine, ivermectin, signaling protein
event_note Published
10/16/2024
blur_on Resolution
3.801 Å
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside
Original publication
import_contacts Title
Glycine receptor mechanism elucidated by electron cryo-microscopy.
import_contacts Journal
Nature 2015
import_contacts DOI
10.1038/nature14853
person Authors
Lu, W., Gouaux, E., Cheng, Y., Wu, S., Du, J.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Lu, W., Gouaux, E., Cheng, Y., Wu, S., Du, J. , provided free of copyright via the Protein DataBank. View original data or read license terms.
