PDB | 3d4s Cholesterol bound form of human beta2 adrenergic receptor.
Cholesterol bound form of human beta2 adrenergic receptor.
label Keywords
gpcr, membrane protein, lysozyme, fusion, adrenergic, timolol, g-protein coupled receptor, glycoprotein, lipoprotein, palmitate, phosphoprotein, receptor, transducer, transmembrane, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, gpcr network
event_note Published
10/30/2024
blur_on Resolution
2.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, CHOLESTEROL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Original publication
import_contacts Title
A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor.
import_contacts Journal
Structure 2008
import_contacts DOI
10.1016/j.str.2008.05.001
person Authors
Griffith, M.T., Chien, E.Y., Roth, C.B., Hanson, M.A., Kuhn, P., Cherezov, V., Velasquez, J., Jaakola, V.P., Stevens, R.C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Griffith, M.T., Chien, E.Y., Roth, C.B., Hanson, M.A., Kuhn, P., Cherezov, V., Velasquez, J., Jaakola, V.P., Stevens, R.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
