PDB | 3aea Porcine heart mitochondrial complex II

Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Dimethylaminomethyl-phenyl)-2-trifluoromethyl-benzamide

label Keywords
respiratory complex ii, inhibitors, electron transport, iron, iron-sulfur, metal-binding, mitochondrion, mitochondrion inner membrane, oxidoreductase, transit peptide, transport, tricarboxylic acid cycle, heme, transmembrane, fad-binding protein, oxidoreductase-oxidoreductase inhibitor complex
event_note Published
10/16/2024
blur_on Resolution
3.39 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, FE3-S4 CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, N-{3-[(dimethylamino)methyl]phenyl}-2-(trifluoromethyl)benzamide, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE

Original publication

import_contacts Title
Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
import_contacts Journal
Int J Mol Sci 2015
import_contacts DOI
10.3390/ijms160715287
person Authors
Ohmori, J., Sato, D., Nagahama, M., Shiba, T., Inoue, M., Balogun, E.O., Sasaki, T., Harada, S., Kita, K., Oda, M., Matsuoka, S., Inaoka, D.K., Honma, T.

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