PDB | 2ydv Thermostabilised HUMAN A2a Receptor

Thermostabilised HUMAN A2a Receptor with NECA bound

label Keywords
receptor, g protein coupled receptor, seven-helix receptor, agonist bound form, thermostabilising point mutations, gpcr, 7tm receptor
event_note Published
11/20/2024
blur_on Resolution
2.6 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
N-ETHYL-5'-CARBOXAMIDO ADENOSINE, octyl 1-thio-beta-D-glucopyranoside

Original publication

import_contacts Title
Agonist-Bound Adenosine A(2A) Receptor Structures Reveal Common Features of Gpcr Activation.
import_contacts Journal
Nature 2011
import_contacts DOI
10.1038/NATURE10136
person Authors
Langmead, C.J., Warne, T., Lebon, G., Bennett, K., Edwards, P.C., Leslie, A.G.W., Tate, C.G.

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