PDB | 2ycy Turkey Beta1 Adrenergic Receptor

TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CYANOPINDOLOL

label Keywords
gpcr, receptor, transducer, antagonist bound form, integral membrane protein, g-protein coupled receptor, thermostabilising point mutations, seven-helix receptor, 7tm receptor
event_note Published
10/23/2024
blur_on Resolution
3.15 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, octyl 1-thio-beta-D-glucopyranoside, SODIUM ION

Original publication

import_contacts Title
Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a {Beta}1- Adrenergic Receptor.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2011
import_contacts DOI
10.1073/PNAS.1100185108
person Authors
Warne, T., Edwards, P.C., Serrano-Vega, M.J., Leslie, A.G.W., Moukhametzianov, R., Tate, C.G., Schertler, G.F.X.

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