PDB | 2x72 Constitutively Active E113Q,D2C,D282C Rhodopsin Mutant

CRYSTAL STRUCTURE OF THE CONSTITUTIVELY ACTIVE E113Q,D2C,D282C RHODOPSIN MUTANT WITH BOUND GALPHACT PEPTIDE.

label Keywords
signaling protein, chromophore, lipoprotein, glycoprotein, transmembrane, retinal protein, g-protein coupled receptor, sensory transduction, photoreceptor protein
event_note Published
11/13/2024
blur_on Resolution
3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, octyl beta-D-glucopyranoside, PALMITIC ACID, RETINAL, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ACETATE ION

Original publication

import_contacts Title
The Structural Basis of Agonist Induced Activation in Constitutively Active Rhodopsin
import_contacts Journal
Nature 2011
import_contacts DOI
10.1038/NATURE09795
person Authors
Oprian, D.D., Fransen, M., Edwards, P.C., Xie, G., Standfuss, J., Schertler, G.F.X., Dantona, A.

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