PDB | 2qju Crystal Structure of an NSS Homolog with Bound Antidepressant
Crystal Structure of an NSS Homolog with Bound Antidepressant
label Keywords
neurotransmitter, transmembrane transport, integral membrane protein, antidepressant, nss, transport protein, structural genomics, psi-2, protein structure initiative, new york consortium on membrane protein structure, nycomps
event_note Published
07/09/2007
blur_on Resolution
2.9 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
octyl beta-D-glucopyranoside, SODIUM ION, CHLORIDE ION, LEUCINE, 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE
Original publication
import_contacts Title
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.
import_contacts Journal
Science 2007
import_contacts DOI
10.1126/science.1147614
person Authors
Zhou, Z., Goetz, R.M., Wang, D.N., Law, C.J., Karpowich, N.K., Zhen, J., Reith, M.E.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Zhou, Z., Goetz, R.M., Wang, D.N., Law, C.J., Karpowich, N.K., Zhen, J., Reith, M.E. , provided free of copyright via the Protein DataBank. View original data or read license terms.
