PDB | 2q7m Crystal structure of human FLAP with MK-591
Crystal structure of human FLAP with MK-591
label Keywords
mapeg, membrane protein, flap, lipid transport
event_note Published
02/21/2024
blur_on Resolution
4.25 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
3-[3-(TERT-BUTYLTHIO)-1-(4-CHLOROBENZYL)-5-(QUINOLIN-2-YLMETHOXY)-1H-INDOL-2-YL]-2,2-DIMETHYLPROPANOIC ACID
Original publication
import_contacts Title
Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.
import_contacts Journal
Science 2007
import_contacts DOI
10.1126/science.1144346
person Authors
Evans, J.F., Ferguson, A.D., Spencer, R.H., Xu, S., Cunningham, B.R., Becker, J.W., Yamin, T.T., Miller, D.K., Ujjainwalla, F., Wisniewski, D., McKeever, B.M., Chu, L.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Evans, J.F., Ferguson, A.D., Spencer, R.H., Xu, S., Cunningham, B.R., Becker, J.W., Yamin, T.T., Miller, D.K., Ujjainwalla, F., Wisniewski, D., McKeever, B.M., Chu, L. , provided free of copyright via the Protein DataBank. View original data or read license terms.