PDB | 2q7m Crystal structure of human FLAP with MK-591

Crystal structure of human FLAP with MK-591

label Keywords
mapeg, membrane protein, flap, lipid transport
event_note Published
02/21/2024
blur_on Resolution
4.25 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
3-[3-(TERT-BUTYLTHIO)-1-(4-CHLOROBENZYL)-5-(QUINOLIN-2-YLMETHOXY)-1H-INDOL-2-YL]-2,2-DIMETHYLPROPANOIC ACID

Original publication

import_contacts Title
Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.
import_contacts Journal
Science 2007
import_contacts DOI
10.1126/science.1144346
person Authors
Evans, J.F., Ferguson, A.D., Spencer, R.H., Xu, S., Cunningham, B.R., Becker, J.W., Yamin, T.T., Miller, D.K., Ujjainwalla, F., Wisniewski, D., McKeever, B.M., Chu, L.

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