PDB | 2muw NOE-based model of the influenza A virus N31S mutant (19-49) bound to drug 11
NOE-based model of the influenza A virus N31S mutant (19-49) bound to drug 11
label Keywords
drug design, m2, viral protein
event_note Published
05/15/2024
filter_center_focus Method
SOLUTION NMR
add_circle Ligands
(3s,5s,7s)-N-[(5-bromothiophen-2-yl)methyl]tricyclo[3.3.1.1~3,7~]decan-1-aminium
Original publication
import_contacts Title
Flipping in the Pore: Discovery of Dual Inhibitors That Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel.
import_contacts Journal
J.Am.Chem.Soc. 2014
import_contacts DOI
10.1021/ja508461m
person Authors
Wang, J., Wu, Y., DeGrado, W.F., Pinto, L.H., Ma, C., Gianti, E., Jo, H., Klein, M.L., Fiorin, G., Canturk, B., Lamb, R.A.
copyrightData provided by Research Collaboration for Structural Biology, Wang, J., Wu, Y., DeGrado, W.F., Pinto, L.H., Ma, C., Gianti, E., Jo, H., Klein, M.L., Fiorin, G., Canturk, B., Lamb, R.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
