PDB | 2drd Multidrug transporter reveal a functionally rotating mechanism

Crystal structure of a multidrug transporter reveal a functionally rotating mechanism

label Keywords
membrane transporter, membrane protein, multidrug efflux, drug resistance, transporter, exporter, antiporter
event_note Published
03/13/2024
blur_on Resolution
3.1 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE

Original publication

import_contacts Title
Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
import_contacts Journal
Nature 2006
import_contacts DOI
10.1038/nature05076
person Authors
Nakashima, R., Matsumoto, T., Murakami, S., Yamaguchi, A., Yamashita, E.

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